GIFT is an assisted reproductive technology which was developed in 1984 as a variation of the IVF procedure. GIFT can be a successful alternative for couples with unexplained infertility provided that the woman has at least one open fallopian tube.

GIFT may be used in patients where infertility is caused by cervical or immunological factors, mild endometriosis, older women, and in some cases of moderate male infertility. GIFT also represents an alternative for patients whose religious beliefs prohibit conception outside of the body. Our fertility specialists will discuss your treatment options so please let your physician know if you are interested in GIFT.

In the GIFT procedure, fertilization takes place within the fallopian tube and this is also where a limitation of the procedure is evident. In IVF, fertilization occurs "outside" of the body. Unfortunately, GIFT does not allow for confirmation of fertilization because it occurs inside the body. The stages involved in the GIFT procedure are very similar to IVF; however, GIFT is more expensive because it requires a laparoscopy.

Steps in the GIFT Technique

1. Ovarian stimulation and monitoring: The initial steps of the ART procedures are the same. The patient takes hormonal medications to stimulate the ovaries to encourage the development of multiple oocytes. The patient is followed during this phase of treatment with ultrasounds and estradiol hormone measurements.

2. Egg retrieval: With GIFT, our doctors retrieve the eggs through transvaginal ultrasound aspiration. The sperm is prepared in advance and the eggs are examined microscopically and then combined with the sperm in a special catheter.

3. Gamete transfer: The gametes (sperm and eggs) are transferred using a laparoscope. The catheter is inserted into the fallopian tube(s) and the sperm and egg are placed directly into the tube. Hopefully, the transferred gametes will fertilize and the developing embryos will then move to and implant in the uterus.